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8-Hydroxyquinoline MSDS

1 Basic information

Chinese Name: 8 – hydroxyquinoline

Chinese alias: 8 – quinoline hydroxide 8 – hydroxy naphthalene nitrogen, ortho hydroxy nitrogen (Miscellaneous) naphthalene, oxine , 8 – hydroxy-naphthyridine

Name :8-Hydroxyquinoline

English Name :8-Hydroxyquinoline; 8-Oxychinolin; 8-Quinolinol; Oxine

Grade: AR

CAS Number :148 -24-3

Formula: C9H7NO

Molecular Weight: 145.16

CAS Number :148 -24-3

No. MDL: MFCD00006807

EINECS No. :205 -711-1

RTECS Number: VC4200000

BRN No.: 114512

PubChem number: 24855220

2 Characters

White or light yellow crystal or crystalline powder , insoluble in water and ether , soluble in ethanol , acetone, chloroform , benzene or dilute acid, can be sublimated. Less corrosive. Low toxicity, LD504800mg/kg.

3 Quality Standards

Name (content and impurity content%)

Index

Result

8 – hydroxy quinoline (C9H7NO) content ≥

99.5

99.7

Melting point ℃

73.0 ~ 74.5 (1 ℃)

73.1 ~ 74.0 (1 ℃)

Sensitivity tests for magnesium

Qualified

Qualified

Acid dissolution test

Qualified

Qualified

Residue on ignition (as sulfate) ≤

0.02

0.015

Chloride (Cl) ≤

0.002

0.0015

Sulfate (SO4)

0.01

0.006

4 Physical Parameters

[1]

Melting point (º C): 75 ~ 76

Boiling Point (º C): 267

Density: 1.03

5 Quality Specifications

Purity: ≥ 99%

Melting point ≥ 75 ℃

Residue on ignition (as sulfate): ≤ 0.02%

Chloride : ≤ 0.002%

Sulfate: ≤ 0.01%

Magnesium sensitivity test: pass

Acid dissolution test: pass

6 dissolved

Soluble in ethanol , acetone, chloroform , benzene, and a mineral acid, almost insoluble in water .

8 – hydroxy quinoline is bisexual, soluble in strong acid , alkali, alkali ions in ionization, can be combined in acid hydrogen ions in PH = 7时solubility minimum.

7 toxicological data

1 Acute toxicity: rat oral LD50: 1200 mg / kg; mouse oral LC50: 20 gm / kg;

Intraperitoneal LD ​​rat: 43 gm / kg; mouse subcutaneous LCLo: 83600 ug / kg.

2 inhalation toxicity: rat:> 1210 mg/m3/6H

The substance may be hazardous to the environment, the water should be given special attention.

8 molecular structure data

1, the molar refractive index: 44.06

2, molar volume (m3/mol): 115.2

3, parachor (90.2K): 320.2

4, the surface tension (dyne / cm): 59.7

5, the polarization rate (10-24cm3): 17.47

9 computational chemistry data

A hydrophobic parameter calculation reference value (XlogP): 2

2, the number of hydrogen bonds for the body: 1

3, the number of hydrogen bond acceptors: 2

4, rotatable bond: 0

5, topological molecular polar surface area (TPSA): 33.1

6, the number of heavy atoms: 11

7, the surface charge: 0

8, the complexity: 138

9, the number of atomic isotopes: 0

10, determines the number of atoms stereocenter: 0

11, the number of uncertain atom stereocenter: 0

12, determines the number of bond stereocenter: 0

13, the number of uncertain bond stereocenter: 0

14, the number of covalent bond unit: 1

10 synthetic

1 o-aminophenol by cyclization reaction. Glycerol was added to the acid reaction pot, stirring slowly adding concentrated sulfuric acid, while the o-aminophenol , o-nitrophenol were added sequentially, fuming sulfuric acid to join the 65% of the total. Heating up to 125 ℃, heating was stopped and warm naturally to 140 ℃, when the temperature was returned to 136 ℃. The rest continues oleum added maintaining the temperature at 137 ℃. After the addition of acid, heat 4h, cooling to 100 ℃, 10 times the amount of pumped water bloom (in o-phenol) acid pot was stirred and heated to 75-80 ℃, with 30% sodium hydroxide solution to a pH of 7-7.2. The precipitate was discharged hot, cooling blocks, sublimation under reduced pressure, to give 8 – hydroxyquinoline products.

2 o-aminophenol, o-nitrophenol, glycerol , acetic acid mixture of concentrated sulfuric acid was added, and the mixture was heated to boiling until the beginning. And then refluxed on an oil bath to remove unreacted nitrophenol by steam distillation. Cooled, neutralized with sodium hydroxide solution and recovered by steam distillation, i.e., to give 8 – hydroxyquinoline.

3 of quinoline sulfonated get 8 – quinoline sulfonic acid groups, and then after alkali fusion get 8 – hydroxy quinoline bases, and finally by acidification to give 8 – hydroxy quinoline. Preparation process is as follows:

① sulfonation quinoline as raw materials in the raw material was added slowly with stirring to sulfuric acid in a sand bath heated at 100 ~ 180 ℃, sulfonated 2 ~ 3h. Then cooled to room temperature, then further cooled ice, filtered dried to give product 8 – quinoline sulfonic acid.

② alkali melt process under stirring, the sulfonated product was added slowly to the molten base, in the melt of about 200 ~ 240 ℃ 30 ~ 40min, cooled water was added and heated to dissolve all the cooling to room temperature After acid and then neutralized to pH = 7, upon crystallization, filtration, the filter cake was dry.

③ The alkali fusion product distillation process using steam distillation, cooling and crystallization is the product 8 – hydroxy quinoline.

11 The main purpose

1, is widely used for the determination and separation of metals. Precipitating agent and precipitation and separation of metal ions in the extraction agent, with the following metal ions: Cu +2, Be +2, Mg +2, Ca +2, Sr +2, Ba +2,?????? Zn? +2, Cd? +2, Al? +3, Ga? +3, In? +3, Tl? +3, Yt? +3, La +3, Pb? +2, B? +3, Sb ? +3, Cr? +3, MoO? +22, Mn? +2, Fe? +3, Co? +2, Ni? +2, Pd? +2, Ce? +3

1 used as pharmaceutical intermediates, synthetic grams Xie Li Ning, clioquinol, flutter respite sensitive materials, but also dye, pesticide intermediates. The product is a halogenated quinoline class of anti-amoebic drug intermediates, including quinoline iodoform, clioquinol, iodoquinol so on. These drugs inhibit the intestinal commensal bacteria play a role in anti-amoebic of amoebic dysentery effective, no outside influence on intestinal amoeba. Foreign reports this class of drugs can cause subacute optic neuropathy, the drug has been disabled in Japan and the United States, caused by the disease iodoquinol than clioquinol rare. 8 – hydroxy quinoline also dye, pesticide intermediates. Copper sulfate and is an excellent antiseptic, disinfectant and fungicide. The product is a complex indicator for chemical analysis.

2 is used as a complexing agent and an extractant precipitation and separation of metal ions, with Cu +2, Be +2, Mg +2, Ca +2, Sr +2, Ba +2, Zn? +2, Cd + 2, Al +3, Ga +3, In +3, Tl +3, Yt +3, La +3, Pb +2, B +3, Sb? +3, Cr +3, MoO? +22, Mn + 2, Fe +3, Co +2, Ni +2, Pd +2, Ce +3, and other metal ions. Determination of organic trace analysis of nitrogen heterocyclic organic synthesis. Also dyes, pesticides and halogenated quinoline class of anti-amoebic drug intermediates. Copper sulfate and is an excellent antiseptic .

3 of epoxy adhesive can be added to improve the metal (especially stainless steel) adhesive strength and heat aging resistance, the amount is generally 0.5 to 3 parts. Halogenated quinoline class of anti-amebic drugs intermediates, pesticide, dye intermediates. Complexometric titration can be used as an antifungal agent, a preservative and industrial polyester resin, phenol resin, and a hydrogen peroxide stabilizer, or a chemical analysis indicator .

(4) The product is an intermediate halogenated quinoline drugs, but also dyes, pesticide intermediates. Copper sulfate and is an excellent antiseptic, disinfectant and fungicide. Cosmetics maximum allowable content (mass fraction) was 0.3%, sunscreen products and products for children under 3 years of age (as talcum powder) is disabled and should indicate on the product label “disabled children under 3 years of age.” In dealing with bacterial infections and bacterial infections of the skin, eczema, lotion 8 – hydroxy quinoline mass fraction of 0.001% to 0.02%. It is also used as a disinfectant, antiseptic and fungicide, and its strong anti-fungal effect. 8 – hydroxyquinoline sulfate used in skin creams and lotions content (mass fraction) of 0.05% to 0.5%.

12 Risk Phrases

R22 Harmful if swallowed.

R37 Irritating to respiratory system.

R38 irritating to the skin. [2]

13 storage transport

Dark dry and ventilated place

14 Hazard statement

Dangerous code: Xn

Dangerous Level: 22

 

Mexican traders want to export to Asia ethylene

Due to weak European markets , Asian ethylene prices are relatively high, Mexican ethylene traders plan in mid- April exports of nearly 4,000 tons of ethylene to Asia. However, insiders said , because it is difficult to rent a boat , the possibility of such a successful transaction is relatively small.

Mexico usually ethylene exports to Europe countries, such as Belgium. Pulitzer data show that exports of 4,000 tons of goods from Mexico to Europe, shipping is about $ 250 / t . The traders and brokers have said that Mexico needs to Asian Maritime month , is expected to take at least a freight around $ 400 to 500 / t. So, Mexico ethylene CFR South East Asia prices of $ 1320 ~ 1420 / ton , while the price of $ 1170 CIF Northwest Europe / ton.

There are traders said , even though arbitrage can play a role , it is difficult to find a suitable freighter . Because this is not a typical route, the owners may be reluctant to take such a risk . Moreover , traders do not want to turn back when the boat is empty.

However , there are a case of 9000 tons of cargo in Europe want to export to Asia in June , has yet to offer, but the seller said to bid $ 1,350 / ton (CFR, Northeast Asia ) . Market participants said the deal reached Europe to Asia is unlikely , since the second half of this year is expected to be very adequate supply in Asia .(http://www.lubonchem.com supply)

Spirulina

A morphological
Spirulina no non Sheath surface , can not easily be attached to the microorganism , the cell bubbles , floating resistance. Top cells or filaments often not shrill , often not obvious transverse wall , top round cells , the outer wall is not thickened. No sex cells and thick-walled cells can multiply to form blooms .
Cyanobacteria cells in the body without pigment , pigment distribution in protoplasts external pigment area , blue and green. Protoplast inside a colorless central area , like other algae nuclei , but no nucleoli and nuclear membrane , and therefore belong Spirulina prokaryotic plants. Spirulina platensis is a filamentous , helical filaments , no transverse walls , blue and green ; filaments 4 to 5 microns wide , length 400 to 600 microns ; algae silk top cell obtuse, no heterocyst .
History

I believe the first use of Spirulina as food was in the sixteenth century, the Aztecs of Mexico , according to the description Hernán Cortés · soldiers , when they picked spirulina and as chief of the lake from Fernandez Pizza sale . The Aztecs called it the ” special crisp Tel off children ,” meaning stone excrement . Spirulina discovered in the 1960s by a French scientist , but not as a food display purposes. The first large-scale production of Spirulina machine is there in the 1970s established
Spirulina in Chad has a very long history , the earliest retroactive nine centuries Kanem – Bornu Empire. They will still be eating today , drying became known as “Dihé” pizza , used to make broth purposes , and will be sold in the marketplace . Spirulina is like Lake Chad from the collection .
Discovery history
The early 1960s , the French explorer Christopher door when Dr. Dement African adventure, discovery Chad lake in Nimes good animal protein deficient even under conditions of inadequate food vegetables still life physically strong, energetic, health and longevity . After the survey found they often fish floating on Lake Chad dried spirulina food and medical treatment .
2 Reproduction editor
Spirulina reproduction of two kinds:

For the vegetative propagation , including direct cell division ( ie fission ) , groups rupture and filaments produced several ways Hormogonia so on.
Spirulina can be generated for some endogenous or exogenous spores spores to be asexual spores without flagella . Spirulina is sexual reproduction has not yet found .

3 ecological conditions

Salinity: Spirulina a grows in alkaline water , can be domesticated cultured in normal seawater.
Temperature : the optimum range between 30 ~ 37 ℃.
Light: optimum light intensity between about 30,000 to 35,000 lux.
PH : The optimum range between about pH8.6 ~ 9.5.

4 health effects editor
Lower cholesterol
Cholesterol lowering can effectively prevent the onset of heart disease and stroke , spirulina in the Y- linolenic acid can lower cholesterol contained in the body , which can effectively reduce blood pressure and prevent heart disease, reduce cholesterol.
Regulate blood sugar
Spirulina contains nutrient-rich , alkaline foods, nutritional supplements can be changed to give the body acidic , adjust metabolic activity . Jane and Joan Ganoderma with food, can regulate blood sugar, diabetic condition for stability has a significant effect.
Immune system
Natural Spirulina phycocyanin contained within , can enhance immune function of human cells , thereby enhancing our body ‘s immunity and disease resistance.
Protect the stomach
Most patients with stomach hyperacidity are led gastritis, gastric ulcer and other diseases , and Spirulina is an alkaline food , the Spirulina contains high vegetable protein and rich in chlorophyll , β- carotene, these nutrients neutralize gastric acid and gastrointestinal mucosal repair , regeneration and normal secretory function is extremely effective , especially for gastrointestinal patients.
Treatment of Anemia
Iron deficiency anemia is a very common phenomenon, and Spirulina is rich in iron and chlorophyll , these nutrients can effectively improve the human condition of anemia .
5 Nutrition Introduction
Nutritional value

Spirulina is rich in protein , up to 55-75 %, which is three times that of beef , eggs six times , 10 times that of rice .
Spirulina is rich in β -carotene , 15 times carrots , spinach 40-60 times .
Spirulina is rich in vitamins B1, B2, B5, B6, B11, B12, C, E. A wide range of B vitamins , but each with specific physiological functions , the lack of any kind which are likely to cause disease.
Spirulina contains a variety of essential trace elements , calcium, magnesium , sodium, potassium, phosphorus , iodine, selenium, iron, copper, zinc , etc., can cause iron deficiency anemia , zinc deficiency can lead to stunted ; selenium can activate DNA repair enzymes, immunoglobulins , and stimulate the production of antibodies to capture free radicals , reduce toxicity in vivo or resistance to certain metals , inhibiting the carcinogenic effects of some carcinogens . Selenium can prevent altitude sickness .
Spirulina contains chlorophyll A, has its unique clean blood hematopoietic function .
1 gram of spirulina nutrients sum equivalent to 1,000 grams of various types of vegetarian nutrients, is a most nutritious nutrients

Spirulina cell wall is very thin, the thickness of only 40-60 nm, and is constituted by a peptide glucan , easily digested and absorbed degradation .

Spirulina contains high γ linolenic acid , can promote calcium absorption , enhance immunity, prevent metabolic disorders and prevent aging functions. γ linolenic acid is the precursor of prostaglandins , in effect becomes dioxygenase prostaglandins , prostaglandin on the reproductive , cardiovascular , respiratory , digestive and nervous system have a role .
Spirulina polysaccharide , anti- radiation function, and by enhancing the body’s immune system. Also Spirulina polysaccharide can enhance the activity of SOD in plasma , reducing the generation of lipid peroxides , have anti-aging effect .

Effectiveness of the role
1 , to stimulate the rapid growth of the body : Spirulina is rich in lysine , threonine and other essential amino acids, for infants and young children , especially the lack of breastfed infants is extremely important. Rich in minerals and trace elements can effectively prevent nutritional anemia , but also eclipse supplementary source of good nutrition for children , can gradually correct the partial eclipse of bad habits.
2 , balanced nutrition growing youth development : the teenagers in puberty , is much larger than the required nutrients adults , plus learn heavy physical exertion great sport , can easily cause recessive undernourished , stunted growth , memory loss, vision loss . Spirulina can provide adequate and balanced variety of nutrients , is well absorbed .
3 adults maintain a strong effort : significantly accelerate the pace of modern life , diet tends to simple, convenient, frequent ingestion of excessive delicacy , so the accumulation of fat in the body , blood acidic, plus social activities , work stress, rest disorder, no time to exercise, excessive alcohol and tobacco , etc., will result in the body’s metabolic disorders, often feel lack of energy , fatigue, drowsiness , decreased immunity . Spirulina can regulate the body’s pH, chlorophyll can purify the blood , remove toxins and clean the rectum , various amino acids , vitamins, minerals and trace elements contained in the function of internal organs can be enhanced .
4 , anti- aging elderly : The main reason is to generate human aging in the metabolism of a large number of oxygen free radicals, which damage the body strong molecular structure of life , leading to cell function decline and accelerate human aging . Spirulina has a variety of anti-aging substance . Such as β- carotene, vitamin e, γ- linolenic acid , and superoxide dismutase , these substances cleared by antioxidant effects of free radicals , effectively delaying cell aging, while Spirulina is rich in iron, calcium, and easy to absorb of anemia common in the elderly , osteoporosis , hypertension, arteriosclerosis, lumbar and leg pain has a good supporting role in prevention .
5 , weight loss , skin care , beauty : Spirulina is rich in nutrients, 1 hour before taking spirulina, spirulina phenylalanine can suppress appetite, relieve diet brings hunger, suffering malnutrition so that people lose weight while still maintaining vitality. Keep the skin soft and shiny appearance of the fundamental factors are balanced nutrition. β- carotene , superoxide dismutase and γ- linolenic acid on skin physiology to maintain flexibility, eliminate stains , improve skin inflammation effectively .
The main ingredient
Nutrients per 100 grams of Spirulina

General Ingredients

Protein

50-75g
Carbohydrates

10-30g

Fat

2-6g

Fiber

0.5-1.5g

Carbohydrates

10-30g

Natural pigment

Chlorophyll

800-1200mg
Carotenoids

200-600mg

Blue algae class

3000-6000mg

Natural minerals

Calcium

25-200mg
Iron

15-200mg

Zinc

3-10mg

Magnesium

200-600mg

Germanium

2-4μg

Selenium

5-20μg

Natural Vitamins

β- carotene

100-200mg
Vitamin B1

100-300μg

Vitamin B2

3-10mg

Vitamin B6

100-300μg

Vitamin B12

1-3μg

Vitamin C

10-80mg

Vitamin E

2-10mg

Niacin

4-30mg

Folate

50-100μg

Pantothenic acid

0.5-1.5mg

Other

γ- linolenic acid

0.5-1.6g
Spirulina polysaccharide

2-6g

Docosahexaenoic acid

0.2-1g

Superoxide dismutase activity

10-37.5 million units

Coenzyme Q10 activity

5-20 million units

Chemical composition
Containing protein ( 60% ) , mainly by isoleucine (isoleucine), leucine (leucine), lysine (lysine), methionine (methionine), phenylalanine (phenylalanine), threonine (threonine) tryptophan (tryptophane), valine (valine) and other components. In addition, fat , carbohydrates, chlorophyll , carotenoids , phycocyanin , vitamins (vitamin) A, B1.B2.B6.B12.E, niacin (nicotinic acid), creatine (creatine), γ- linolenic acid (γ-linolenic acid), calcium pantothenate , folic acid (folic acid) , calcium , iron, zinc and magnesium.
6 major categories
Spirulina is a total of 35 species belonging to the taxonomic status of Cyanophyta , Cyanobacteria Gang , head chatter algae , algae flutter Branch, spirulina is . Commonly used in the cultivation of Spirulina platensis, Spirulina maxima and Spirulina salt marshes . As health care is mainly consumed Spirulina maxima ( scientific name Arthrospira maxima) and Spirulina platensis ( scientific name Arthrospira platensis). The two species that had previously been divided into Spirulina ( scientific name Spirulina), after sub- section spiral into algae genus, but the habit is still referred to as ” Spirulina .”
Spirulina maxima
Like other blue-green algae , Spirulina maxima cells did not really within the nucleus , compared with platensis, filaments longer, wider pitch , but not as good as the nutritional value of Spirulina platensis high .
Spirulina platensis
Spirulina platensis is usually blue-green, multi- cell type, cylindrical helical filaments , solitary or clustered together students , algae wire diameter 5-10μm. Nearly square cells , cell width 6-8 microns, 2-6 microns long , apex obtuse , spiral count 2-7 . The end is not tapered or slightly thin, the end of the round cells wide , horizontal wall closed slightly constricted , no particles cross the wall . Frond can vibrate and rotational motion , often around a vertical axis as quickly rotate forward crawling. Cell contents even without a true nucleus. Due to the different number of in vivo phycoerythrin and phycocyanin , etc. , and show different body color , such as blue- green , yellow-green or purple and so on. And a delicate cross next door.
7 known origin

The world’s natural spirulina can grow naturally the four lakes , Lake Chad in Africa (Tchad Lake), Lake Texcoco , Mexico (TexcocoLake), Lijiang, Yunnan, China Chenghai Lake and Ordos Hammamet too alkaline lake. After years of publicity, high profile , but the actual remaining Chenghai Lake and Lake still remain too alkaline Hama production, two other lake almost dried up. Chenghai Lake in the vicinity of the affected residents , Chenghai Lake protection has been put on the agenda . Hama no industrial pollution too alkaline lake , abundant groundwater resources , water quality , coupled located at latitude 39 degrees , adequate light and heat resources , which provides favorable conditions for the production of Spirulina .
8 taking Notice

Avoid greasy foods.
Generally middle-aged , diabetes, gastrointestinal diseases, health and beauty dieters half an hour before or one hour on an empty stomach ; puberty before , cancer, anemia, major surgery, trauma large , poor physical and emaciated after meals.
In accordance with the usage and consumption , children and pregnant women should be taken under the guidance of doctors .
Taking medication during the two weeks or no improvement of symptoms , or the symptoms get worse , or the emergence of new serious symptoms should be discontinued immediately and go to the hospital .
Drugs ban taking property changes.
Children must be under adult supervision.

9 healthy eating Editor
1 . Daily health 2-3 times daily, every 2 g , 30 minutes before meals . Usually ready to take clothing.
2 . Fatigue 2-3 times a day , every 2-4 grams, 30 minutes before meals . Take 2 grams plus special fatigue.
3 . Rapid weight loss diet, three times a day , each 10 grams, taken 60 minutes before meals , drink beans in the morning

Add a small amount of pulp or milk foods fruits and vegetables , lunch plus the amount of about 120 grams of staple food dish , dinner plus the amount of about 100 grams of staple food dish . Ordinary diet, three times a day , every 4 grams , taken 60 minutes before meals , reducing food intake than usual 1/3-1/2 . If the soup , to the meals , eat greasy food.
4 . Poor health three times a day, every 3 g , 30 minutes before meals .
5. Poor resistance 3 times a day , every 3 g , 30 minutes before meals .
6. Malnutrition emaciated 3 times a day , every 2-3 grams, 30 minutes before meals . For those fattening meal 15-30 minutes to take.
7 . Anti-radiation 2-3 times a day , every 2 g , 30 minutes before meals .
8. 3 anti-aging day, every 2-3 grams, 30 minutes before meals .
10 major products
Spirulina products come in many forms , spirulina powder with fruit , edible vegetable sauce mix , tablets, capsules, spirulina extract concentrates and other refined easy access at any time .
Spirulina powder
Spirulina powder is uniformly dark green or blue -green, 100% pure powder no variegated particles may be appropriate to add to many dishes to increase their protein and vitamin content . Spirulina powder soup , bread, salad taste good , not much to give the food consumption of pink dyed dark green . Like many natural foods like spirulina , heat will destroy its rich nutrients , so when making food less heat as possible.
Enjoy spirulina powder easiest way is to add it in the blender or food in your favorite fruit, juice , and consumption from less to more , and gradually adapt. Many who eat it every time you drink eat 10 grams of spirulina powder.
Some useful suggestions :
① Do not wet spoon into his spirulina powder bottle , or a spoonful of spirulina powder directly into the liquid to be added slowly while stirring to avoid condensation.
② dry spirulina powder will absorb moisture, need to tighten the cap after use .
③ without the fridge, but it should be placed in a cool , dry, dark place .
Within 30 minutes after eating spirulina powder , the human body will react , especially since the powder is easy to digest and absorb. Spirulina drinks once or twice , will be able to promptly provide energy and nutrients ( or replace meals between meals ) a day.

Anti-anoxia, anti-fatigue
Product function

Effective in improving the symptoms of stomach , diarrhea and constipation against a variety ;
Prevention and treatment of anemia, carotenoid content is 1.5 times carrots , four times the vitamin B12 content of the liver , the iron content is 23 times the spinach ;
Containing the body’s own synthesis of linolenic acid , helping fat metabolism, prevent thrombosis, effective against cardiovascular disease , prevention of fatty liver and cirrhosis of the liver , lower blood sugar, diabetes prevention ;
Prevention of taking tranquilizers , antibiotics, anticancer agents , such as renal function impairment;

Spirulina tablets and capsules made ​​to make it easier to carry. Most of spirulina tablets containing 200-600 mg, and 400 mg capsules contain or less. Making tablets and capsules , the addition amount of the tableting excipients in the outer sleeve forming or soluble edible film , in half an hour before eating or one hour after meals to tablets or capsules. If certain times of the day feeling low energy , ready to eat a few slices of spirulina, a body generally have a better response two hours later.
Concentrate
Fresh – Liquids: direct extraction of fresh algae , nutrients locked retain activity.
Efficient: cryogenic liquid extraction, retained high activity, absorbed more efficiently . [ 1 ]
11 Identification of the pros and cons
1 . Look mark . For spirulina health food , there must be a formal national health food approval. The information set forth in the product label must comply with the requirements of national standard of health food label specifications . If the list of ingredients , functional ingredients and their contents table , suitable for consumption and taboos crowd of people claiming health functions , taking methods , net content , shelf life, product standards , health permit number , the manufacturer and / or dealer name and The main message address. If any of the major missing information , it shall be questioned. Can be no trademark , no name , no address “three noes ” products, food safety permit access system for national implementation in terms of food have to go through all the “QS” certification mark .
2 . See color . 100% genuine natural spirulina , both powders , tablets, capsules algae powder were tested within the dark green , slightly yellow ( do not look at the surface , but also break apart and look at the cross-section of color ) : pure green Spirulina products , you may have a problem , or shoddy or counterfeit , or a mix of other substances. Because spirulina processed very dry, easy to absorb moisture, the moisture absorption may gradually become green , and easy to spoilage, eat this healthy spirulina not only useless , but harmful .
3 . Smelling odor. Spirulina algae have a special smell or smell of the sea . Without this peculiar smell may not be stored for too long or spirulina algae powder processing of raw materials . However, with the smell of corruption is likely to be inferior products.
4 . Look hardness. Spirulina tablet products for hand breaking it, the harder the more other ingredients spirulina tablets doping , and quality can hand a breaking apart.
5. Tasting. Spirulina has tasted the flavor , usually slightly alkaline taste . If heavier alkali ignorant , is sub-standard . In addition , products made ​​from 100% spirulina , should be relatively sticky mouth .
6. Soluble observation. Spirulina powder or tablet into a glass filled with pure water , and to dissolve, observe the color of water . For quality , water should be green , half an hour later and gradually turns blue .
7 . See packaging. Spirulina nutrients , some with air isolation is needed to save , such as algae blue pigment , carotene. So there must be moisture barrier packaging wet compartment light , the intrinsic quality of the product packaging is the protective layer . Packaging If you do not meet state regulations , likely to cause damage and deterioration Spirulina nutrients. Scientific experiments show that algae blue pigment in direct sunlight for 15 minutes to 50% loss in unsealed condition will basically lost within three months. Therefore, in order to avoid direct contact with light and air , to ensure no loss of nutrients , Spirulina large international enterprises generally use aluminum foil pouch packaging .
In addition , many unscrupulous traders put on the market inferior spirulina seaweed as a sale , consumers need to pay attention to identify. Wakame and spirulina are two different plants, it is easy to distinguish : wakame leaves as big as tea , while Spirulina is a tiny aquatic plant almost invisible to the naked eye , to the aid of a microscope to look 600 times so clear , like the dust was collected .
12 Questions
Quality Protein say
a, high-quality protein to be easily absorbed by the body ( : easy to be broken down for the body to quickly absorb the amino acids) .
b, spirulina high protein content .
c, various proportions of amino acids in the protein content of spirulina is very close to the proportion of the body needs , high utilization . Various human enzymes, the proportion of the various organs of the very demanding requirements of various amino acids . If a particular amino acid deficiency. Other amino acids also play a role and not lost in vain . Its truth is like a bucket from a lot of wood strips , if one of the plates is short , the other the role of boards is also restricted.
Effects on the human body
a, by a variety of human cells. Protein is a major part of cells and tissues , the presence of protein in the form of life . Protein to maintain the growth of cells and tissues , updates and patches , so that the continuity of life .
b, proteins involved in a variety of important human physiological activities. There are a lot of special proteins in vivo function . Such as an enzyme , regulatory protein (immunoglobulin ) , antibodies, peptide hormones. Muscle contraction , material transport by hemoglobin in the blood , etc. to complete protein , a protein which functions can not be replaced by sugar and fat .
c. Protein for the body to provide energy , can produce 4.1 grams of protein per kilo-calories , 18% of adults in the energy supply of the protein.
the role of β- carotene on human health
a, prevention and treatment of iron deficiency anemia. β- carotene can promote iron absorption and utilization , improve hemoglobin index .
b, promote calcium absorption and bone development. Not simply the bones grow and lengthen , but bone cells continue to divide , synthesize into a new shape. β- carotene to maintain a balance of osteoblasts and osteoclasts . Ensure normal growth of bones .
c, photosensitive retinal cells to maintain , enhance vision, night blind disease prevention .
d, to maintain the skin and eyes, respiratory, digestive , urinary tract epithelial tissue integrity and reproductive systems , sound defensive attack bacteria, viruses.
e, stimulated lymphocyte proliferation , protection of T- cells , B- cells and phagocytic cells , anti-cancer , anti-cancer .
f, anti-oxidation, enhance immunity, anti-aging. β- carotene can prevent oxidation and fat cell membranes , preventing hyperlipidemia, preventing normal cell aging, improve immunity, to anti-aging purposes.
The easily absorbed iron
Many plants contain iron , but because of structural problems , it is difficult to be absorbed by the body . Spirulina is rich in iron and iron- based oxygen reduction protein – in the form of the presence of iron porphyrin , easily absorbed by the body. The absorption rate of 60 % higher than normal blood tonic .
National Use
Citizens of the world most developed countries generally eat spirulina. Such as: USA, UK, France , Germany, Japan and so on.
Ingredient
Protein content ( a ) of Spirulina
The protein content of Spirulina can be said to be the highest among the various kinds of food , an amount of 56% -77 % , Chlorella protein content of 40% -56 % of soybean protein is 34 % -40 % milk powder 12% -22 %. It is similar to the pattern of essential amino acids with FAO and the World Health Organization ‘s essential amino acid pattern of preschool children . Its protein efficiency ratio (PER), net protein utilization (NPU), digestibility , biological value (BV) is equivalent to the best food protein , such as eggs, milk, casein or egg albumin.
Vitamin content ( two ) Spirulina
Spirulina vitamin content is also very rich , 1kg Spirulina contains vitamin B1 55mg, Vitamin B2 40mg, vitamin B6 3mg, vitamin B12 2mg, pantothenic acid 11mg, folic acid 0.5mg, Niacin 113mg, Inositol 350mg, Biotin 0.4mg, vitamin E190mg, carotene 4000mg, ( wherein the β- carotene 1700mg).
Mineral content (c ) Spirulina
These are used because of the quality and content of training institutions to another. Average iron content of 580-646mg/kg, manganese 23-25mg/kg, magnesium 2915-3811mg/kg, selenium 0.4mg/kg. Calcium, potassium and phosphorus are 1000-3000mg/kg or higher.
Fat content ( four ) Spirulina
Spirulina approximately 7% of the total fat content , fatty acids, 5.7% , and most of which are polyunsaturated fatty acids. Linoleic acid up 13784mg/kg, γ- linolenic acid is 11980mg/kg. This is the other natural plant foods is very rare.
Carbohydrate content ( five ) Spirulina
Spirulina carbohydrate content is 16.5% , and rich in polysaccharides. Spirulina extract has been reported with dextran for cancer research .
Are there side effects
It is measured in vivo quality spirulina protein content as high as 60 to 70 %, which is three times the fish , meat four times , five times more eggs , and chlorophyll content is 10 times more vegetables. In addition, vitamin B3 is about 6.4 times soybeans ; β- carotene is about four times the normal levels of carrots ; Spirulina contains about 11 kinds of fatty acids , linoleic acid and linolenic acid which are essential fatty acids ; Spirulina contains major and trace elements necessary for humans and animals , not only contains a lot of iron , but also with protein and phycocyanin organic iron chelated form , which is conducive to absorption, while spirulina has enriched selenium, zinc, ability of iodine.
Spirulina is a very wide range of applications , food, medicines, cosmetics and other fields are applied.

Health Food

Spirulina is rich in high quality protein , vitamins , minerals and other bioactive substances , and its cell wall composed of polysaccharides , easily digested ( 86% digestibility ) , called the best natural green health food .
2 . Fitness and diet food
Spirulina as a diet food in the United States , Europe and other countries has become a trend, the method is 30 minutes before eating or one hour dose of several grams of spirulina can suppress appetite, leaving the reduced food intake , so that neither the lack of nutrition and physical can reduce caloric intake to achieve weight loss purposes.
Of particular importance is that it is rich in iron , and in the diet of women often find iron deficiency .
3 treatments
( 1 ) can be used as anti- radiation damage drugs
( 2 ) can be used for cancer radiotherapy and adjuvant chemotherapy
( 3 ) can effectively reduce blood lipids. A bioactive substances contained within Spirulina – Spirulina polysaccharide and γ- linolenic acid , have the function of regulating the body lipids and prevent atherosclerosis and coronary heart disease adjuvant therapy .
( 4 ) can effectively enhance immunity
( 5 ) Other treatment : Spirulina can effectively prevent the occurrence of cancer . Meanwhile , spirulina for the treatment of diabetes , hypertension , fatty liver, iron deficiency anemia, pancreatitis , ulcer , inhibition of renal impairment has a good effect.
4 Cosmetics
Containing active substances extracted from Spirulina cosmetics , increase skin elasticity , skin moisturizer , wrinkle , freckle and other effects ; can promote skin metabolism, and reduce scarring ; same time as Spirulina cosmetics good permeability , can play the skin surface and deep nutrition and the role of nursing , and is very safe to use on skin without irritation and sensitization.
Earliest Spirulina is used in cosmetics in France . Add spirulina mask, hair care , skin care creams are expensive but very popular. China also has a similar product .
Microcystin
About microcystin (MC) of public health articles , causing everyone’s attention , even to the extent that it was already scared .
The study found that as a liver cancer MC accelerator, a low dose may cause liver damage, which can activate oncogenes body while suppressing cancer genes that make cancer gene inactivation , increase the possibility of cancer nearly 10 times.

In fact, Microcystis in natural waters is widespread , if water quality is good, not too serious contamination or pollution is not , then slow the growth of Microcystis , does not produce a lot of harmful MC.
Only when a large number of untreated pesticides , agricultural fertilizers , such as phosphorus detergent into the water body , resulting in super multi nitrogen and phosphorus content in water to form a water eutrophication case, in the face of a suitable temperature (20 ℃ ~ 30 ℃) , plenty of sunshine , which are conducive to growing conditions when Microcystis , microcystin will quickly multiply in a short time , resulting in a large number of MC.
Since most water bodies are polluted conditions exist , therefore the presence of MC becomes a wide , high-impact natural toxicants . According to the survey found that some areas of surface water as a source of drinking water , even in tap water can also be detected in MC.
Therefore, Shanghai Fudan University, Professor Zhang Shun Yu and other experts pointed out: tap water to eliminate the need to strengthen research microcystin technology and to develop drinking water standards as soon as possible in a limited amount of MC .
Experts point out that prevention MC, the most fundamental is controlled from environmental factors , such as maintaining water flow , manage sewage ban phosphorus pollution caused by eutrophication , and to prevent secondary pollution of drinking water , as long as more than a few MC point is do not worry about the pollution caused by damage to the human body .
As a kind of aquatic organisms , some people worry about whether spirulina is microcystin contamination will not affect food safety ? The experts concluded that Spirulina is safe containing MC will not affect food safety.
This is due to the growth of Spirulina and Microcystis environment is conflicting . Spirulina can grow to survive environmental microcystin ; while microcystin waters can grow , and harvest spirulina really difficult to survive .
Spirulina specializing in research for many years experts have also to be sure.
Experts agree that the current production of large enterprises Spirulina is safe, consumers can rest assured that taking , do not worry about their safety .
Use different populations

Old people

Elderly people taking spirulina, 45% is for a specific disease, 28% used to maintain good mental health , 12% is used as a nutritional supplement. Among those for specific disorders , 22 percent in order to increase blood sugar , 15% in order to protect the eyes, 14% compared relieve constipation .
2 Infants
United Nations : 2000 World Breastfeeding rate should reach 80 %. Spirulina can effectively improve serum protein , and rich in vitamins , unsaturated fatty acids and enzymes , can play a good role in natural prolactin .
3 teenagers
Spirulina is rich in nutrients to meet the metabolic needs of growth and development of young people and strong .
4 Women
Spirulina natural nourishing effect and safety in terms of the effectiveness of weight loss in terms of beauty , has been ladies of spirulina widely recognized. Meanwhile , Ms. due to special physiological reasons , many suffering from anemia , and therefore often need iron , iron- rich spirulina , easily absorbed. In addition, long-term use of Spirulina foods can reduce women premenstrual syndrome, female endocrine regulation .
5 Athletes
Spirulina is a basic food for the body to maintain normal blood weakly alkaline, eliminate fatigue effects, to improve the athlete’s endurance , power , and promote athletes to improve physical function had a significant effect .
6 computer personnel
In modern society, let us not hide electromagnetic radiation , especially long-term operation of the computer , people who use mobile phones while Spirulina is recognized as the world’s anti-radiation adjuvant treatment of food .
If the effect is not significant, need to check the following points :

When eating spirulina, whether the case intermittent , or consumption adequacy . (Depending on individual constitution and the environment, taking also vary the amount we recommend taking daily care of about 5 grams a day , taking about 10 grams of rehabilitation per day ) .
Daily diet is inconsistent ( too many acidic foods , tobacco, alcohol , mental stress or irritation ) .
Lack of proper exercise

Some people do not eat spirulina B cards diarrhea , but after eating a brand algae began to diarrhea .
This phenomenon , there are two possibilities, one containing an excess of harmful dinoflagellate fungi, unsanitary ; Second, the quality , but off B algae , dinoflagellates and good quality , causing a better response .
Determine what causes diarrhea because come, there is a simple way is to look after the diarrhea is not a bad effort because of diarrhea caused by unsanitary , can cause people to weakness, even dehydration, but also showed better response although diarrhea , but it does not lead to deterioration of human effort .
Contrast components
· Spirulina soy protein content corresponds to 1.5 times, 10 times that of rice , pork, 4 times , 3 times that of beef , chicken, 3.7 times, 5 times the egg , fish three times , 2.4 times the cheese.
· Spirulina β- carotene content of carrots is 15 times .
· Vitamin B12 content of spirulina is four times the liver .
· Per 100 grams of algae powder , γ- linolenic acid content of up to 1200 mg or more . So far , had been recognized directly edible γ- linolenic acid only human milk and it contains spirulina , spirulina γ- linolenic acid content of human milk is 500 times .
· Spirulina is extremely rich in chlorophyll content is mostly terrestrial plants 2-3 times , is 10 times more common vegetable content .
· Spirulina fat content of only 5 \ % , pork content of 50 \ % , beef content of 24.08 \ % , fish content of 4 \ % , eggs 8.8 \ %.
· Spirulina polysaccharide up to 14 \% -16 \% / g, Ganoderma content of 1.28 \% / g times , aloe content of 1 \% / kg.
13 Aquaculture Technical Editor
Spirulina is one of the oldest autotrophic photosynthetic micro-algae , is lower plants , its body under the microscope spiral named. This ancient sea creatures , like high temperature (25 ℃ ~ 36 ℃), high alkaline (PH9-11) in the growth environment, many organisms , bacteria difficult to survive in this environment , and spirulina able growth and reproduction. In particular, it is not only the most nutritious , most comprehensive, balanced nutrition is a true champion on the planet , and high light efficiency , adaptability , growth cycle is very short , fast breeding , particularly high yield , artificial breeding efficiency particularly good prospects very broad.

Spirulina correctly handle the relationship between reproductive and environmental conditions

Spirulina farming is the most important conditions of light , temperature, medium and ventilation . PH value of the culture solution , a reasonable supply of depth, flow , exhaust oxygen and nutrients , are an important factor in yield. Therefore , training should be built in pool water quality is good , light conditions are suitable, spacious venue where ; PH value range is 7-11 , preferably 8-9 ; depth of between 0.2 and 0.3 meters ; temperature 18-38 ℃, the most Fortunately 26-32 ℃.
Two Dian choose suitable breeding species
The main breeding species on the domestic and foreign production of Spirulina platensis ( native to Africa Lake Chad ) and Spirulina maxima ( originating in Mexico ) . Huanghua in Hebei Province of algae scientists found suitable for temperate coastal counties grow Spirulina natural variability strain was identified as Spirulina platensis strain 6 (S6); country and from Chad to introduce Spirulina platensis strain 1 (S1); China has also been bred strains and ST-6 Spirulina Spirulina subsalsa . These varieties ( lines ) , can be selected according to local conditions . S6 suitable for growing in northern China where , and salt marshes Spirulina was adapted to high temperatures, sea salt and algae reproduction .
Three Dian from reality , using different farming methods
1 Family farming. You can buy ” Spirulina family culture system ,” also can choose enamel pots ( best all-white ) or crock pot , but can not use aluminum cone . Person- scale farming should be determined by the amount consumed spirulina . If using a 36 cm washbasin , a child needs 12 , while an adult will need around 20 .
2 simple farming. Mainly refers to the equipment is simple, you can make the best pond , as long as watertight on the line. Pool depth 30 cm , the area should be as some large , according to an adult 1.5m2 meter .
3 natural lakes farming. Originally Spirulina grows naturally in saltwater lakes in the original algae, the use of natural lakes farming is the most original , the most economical mode of production . Its equipment requirements are very low , just invest in the fight floods and processing , the lake ‘s fertility can be restored by nature . But because spirulina on light, temperature , PH value, etc. have special requirements , not all lakes can be farmed , but should experiment , research, and select the appropriate reproductive lakes ( such as our Chenghai Lake in Yunnan Province , etc.), for breeding .
4 . Factory farming . Advanced equipment , the grand scale , demanding. Currently, the breeding pool to runway style oval concrete ponds as well ; farming area of ​​15,000 m2 is best as a unit . Training can be open , but also for closed production . Open Training is a near-natural production methods, the system of freshwater , sea water system , most pools are designed to train circulation , stirring with a mixer , the depth of the liquid culture for 15-25cm, with sunlight as the light and heat sources . Closed production means in a closed bioreactor by means of natural light or artificial light be a breeding factory production of Spirulina .

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Povidone iodine (PVPI)

Basic information
【Common name】 povidone- iodine solution povidone-iodine ( iodine naloxone ) PVP is the English abbreviation for Poly Vinyl Pyrrolidone , Chinese name: polyvinylpyrrolidone, is a high performance , versatile sub- soluble compounds, the series Our products are widely used in textile printing and dyeing , pharmaceutical, cosmetics, beverages , adhesives, synthetic resins, detergents, paints, coatings, electronic information materials , bio- engineering materials and water treatment and other fields.
[English name] : Povidone Iodine (PVP Iodine)
[Alias] : Eric , easy speed net , Peavy iodine, pyrrolidone acid, povidone-iodine iodine ; iodine attached ; iodine naloxone ; povidone – iodine ; povidone iodine ; povidone iodine ; polyethylene iodine ; Peavy iodine ; iodine Los ketone ; solid iodine ; povidone-iodine ; Dikang Litai
[ Formula ] : C6H9I2NO (“l” on behalf of the iodine atom )
2 Indications
For suppurative dermatitis, fungal skin infection , a small area of mild burns , but also for a small area of ​​the skin, mucous membrane wound disinfection.
3 Dosage
Can be used for skin disinfection, disinfection of skin and mucous membranes trauma , chronic sore throat , mouth ulcers.
4 pharmacological effects
This product sterilization preservatives, for a variety of bacteria , spores , viruses , fungi and other role in the killing . Its mechanism of action is the product after contact with the wound or lesion, can release free iodine depolymerization play a bactericidal effect . Organization is characterized by irritation , applied to the skin , mucous membrane infections. Can be used in a small area of ​​the skin, mucous membrane wound disinfection.
5 Pharmaceutical Analysis
Method name: povidone-iodine – Determination of povidone iodine – potentiometric titration
Application: This method uses potentiometric titration of iodine povidone-iodine (I) levels .
This method is suitable for the determination of povidone iodine (I) iodine content .
Principle of the method : the test sample add water and stir to dissolve, according to potentiometric titration ( Appendix Ⅶ A), with sodium thiosulfate solution (0.1mol / L) titration , each 1mL sodium thiosulfate solution (0.1mol / L) equivalent to 12.69mg of I.
Reagents: (1) water ( boiling placed to room temperature )
2 sodium thiosulfate solution (0.1mol / L)
3 . Anhydrous sodium carbonate
4 KI
5 benchmark dichromate
6 . Starch indicator solution
7 . Dilute sulfuric acid
Equipment:
Sample Preparation: 1 sodium thiosulfate solution (0.1mol / L)
Preparation: 26g anhydrous sodium thiosulfate 0.20g, add boiling over cold water amount to dissolve into 1000mL, shake , place one month after filtration.
Calibration: dried to constant weight at 120 ℃ baseline potassium dichromate 0.15g, accurately weighed, set the iodine bottle , add water to dissolve 50mL , add potassium iodide 2.0g, gently shake to dissolve , add dilute sulfuric acid 40mL, shake , Mesa, in the dark for 10 minutes, diluted with water 250mL , when using the droplet to near the end , add the starch indicator solution 3mL, continue titration to the disappearance of the blue and visible light green , and titration with blank test correction . Each 1mL sodium thiosulfate solution (0.1mol / L) is equivalent to 4.903mg potassium dichromate . According to the amount of consumption of the liquid taken with potassium dichromate , calculate the concentration of the solution.
When room temperature over 25 ℃, the reaction solution should be diluted with water to cool to about 20 ℃.
2 starch indicator solution
Take soluble starch 0.5g, add water , stir 5mL , slowly pour boiling water into the 100mL , with the added with stirring and continue to boil for 2 minutes , let cool, pour supernatant , that was the solution should be Pro with the new .
3 . Dilute sulfuric acid
Sulfate 57mL, diluted with water to 1000mL.
Procedure : To about 1g, accurately weighed, set the beaker , add water 120mL, stir to dissolve, according to potentiometric titration ( Appendix Ⅶ A), with sodium thiosulfate solution (0.1mol / L) titration , each 1mL sodium thiosulfate solution (0.1mol / L) is equivalent to 12.69mg of I.
Note 1: ” Precision Weigh ” means to check the weight should be accurately referred to take the weight of one-thousandth , ” precise amount ” means to measure the accuracy of the volume should be in line with national standards for the volume pipettes accuracy.
Note 2: ” Moisture ” by drying method, take the test 2 ~ 5g, spread on drying to constant weight , flat, said bottle, no thicker than 5mm, osteoporosis test does not exceed 10mm, accurately weighed , open the bottle at 100 ~ 105 ℃ dried for 5 hours , the cap cover , remove the dryer to cool for 30 minutes, accurately weighed, weight , and then dried in the above temperature for 1 hour, cooled and weighed to twice weighing less than 5mg difference so far . According to weight loss , calculated in the test water content ( % ) .
References: People’s Republic of China , the State Pharmacopoeia Commission Code , Chemical Industry Press , 2005 edition, two , p.823.
6 role and use Edit
Strong broad-spectrum disinfectant against viruses , bacteria , fungi and mold spores have a strong role in the killing . This product is irritating to the skin , low toxicity , lasting effect . Safe and convenient. The basic non-irritating to the organization , for disinfection of the skin and mucous membranes , such as washing before surgery , surgical site and wound disinfection.
Povidone iodine, a 10% solution generally used as a disinfectant . Effectively kill : Newcastle disease, IBD , avian influenza, Mycoplasma , E. coli, salmonella , flu, blue ear disease. Parasite eggs can kill livestock , and can inhibit the breeding of mosquitoes and other insects . And can be used for fruit trees , crops, fish farming them .
7 Features
1 , the compound is a PVP-Ⅰ efficient new disinfectant antiseptic agents, 0.7% to 10 % solution in water to release the 1.8 ~ 24 ppm free iodine by the microbial oxidation of the latter from the killing effect on bacterial killing effect than Xianbi Tai , and has some lethal bacterial spores . Candida albicans drug , showed a significant role in the killing golden grapes bacteria, E. coli, Bacillus subtilis ; against Pseudomonas aeruginosa, Candida albicans sterilization time with the same concentration of compound iodine solution , iodine is similar, but only toxicity for 1 /4 to 1 /9. Compound PVP-Ⅰ toxic side effects, low price, the skin has a protective function of the mucous membrane , which was superior to anti- STD Jieeryin and aqueous potassium permanganate .
2 , in the solvent gradually release iodine , play the role of a sustained release , in order to maintain a longer sterilizing time . Mechanism of its strong sterilizing pathogens puree oxidation activity of the protein group , and capable of binding to denatured protein and amino group , thereby effectively kill bacteria, spores, fungi, protozoa, viruses and other pathogens . Has a strong bactericidal bactericidal wide range of stimulating small , stained yellow light , easy to clean, no allergic reactions and other characteristics.
3 , Staphylococcus aureus , Escherichia coli, Pseudomonas aeruginosa, Neisseria gonorrhoeae , Candida albicans and other hundreds of species of bacteria , viruses and other rapid killing effect. The product is the preferred disinfectant antiseptic drugs currently used for domestic and foreign direct human skin , mucous membranes .
4 , due to the gradual decomposition of the free iodine and work. 80 % – 90 % of the binding free depolymerization iodine iodine pathogen directly in protein denaturation , precipitation, resulting in the death of the pathogen cells to achieve efficient sterilization purposes. Which is characterized by strong bactericidal , low toxicity, and is a broad-spectrum fungicide that can kill viruses , bacteria, spores, fungi and protozoa . Against Staphylococcus aureus , Neisseria gonorrhoeae , Pseudomonas aeruginosa , Treponema pallidum , hepatitis B virus , HIV , Trichomonas vaginalis and others have a strong role in the killing .
5 , topical skin can cause allergic reactions, skin and mucous membrane irritation. Severe burns or large areas of skin exfoliation can cause systemic adverse reactions , such as metabolic acidosis, hypernatremia and renal damage, allergic to iodine , burns covering more than 20% , should not topical application , suffering from non- toxic thyroid tumors NA jelly , pregnant women and newborns should be used with caution large area . Children under 4 years of age is not recommended.
6 , broad spectrum bactericidal , fungicidal and strong, able to directly kill bacteria, fungi , viruses , spores and protozoa . Sterilization speed , most bacteria can kill within 30 seconds , five minutes is sufficient for an individual to kill bacteria . No stimulation of the skin and mucous membranes , can be used to disinfect and treat the body cavity , mucosa and ulcers . Non-toxic. Difficult to make microbes resistant , easy to allergic reactions . Use durable , good stability, long storage period . Soluble in water , easy to clean , no pollution or damage to the fabric and other items .
7 , the product acts as efficient gynecological sterilization products, its pH and vaginal similar, mild , diluted according to the instructions ( warm water ) after the effective capacity of 300ppm iodine , more than bactericidal concentrations 10-20 times , after washing can effectively kill within a variety of pathogenic microorganisms.
8 Use the
1 thermometer disinfection : 3 % concentration soaked for more than 30min , after removing 75% ethanol can be placed in the back , can also be rinsed with sterile water or cold water into the sterile container after use.
2 kinds of glassware disinfection : Available 2% to 3 % concentration soak 1 ~ 2h, due to the effect of having a wash , facilitate cleaning . For items such as carbon steel and aluminum products such as scalpel blades corrosive , not long-term immersion other metal instrument sterilization .
3 skin disinfection : 1 % to 3% scrubbing 2min, as a surgical hand disinfection before or infectious room, infectious disease specialist outpatient medical staff hand disinfection.
4 hot treatment , burn : 0.5 % solution , sprayed on the wound every 12h 1 until eschar separation so far.
5 , routine health care : for bacterial , fungal , trichomonas vaginitis , cervicitis, cervical erosion treatment. For the prevention of sexually transmitted diseases (STD), such as gonorrhea , syphilis, AIDS. Intercourse before and after menstruation clean the vagina . Gynecological surgery sterilization , disinfection before vaginal childbirth .

sodium metabisulphite

A detailed description editor
Basic Information
Name
English / Latin names
Sodium Pyrosulfite
Jiaoya Liusuanna
English Name

Supplies: http://www.lubonchem.com
: SODIUM BISULFITE; disodiummetabisulfite; disodiumpyrosulphite; fertisilo; metabisulfitedesodium; Sodiummetabisufite; sodiummetabisulfite (na2-s2o5); sodiumpyrosulfite (na2s2o5); Sodium dissulfite; Sodium disulphite; Sodium pyrosulphite; SODIUM METABISULFITE, PH EUR; SODIUM DISULFITE DRY TECHNICAL; SODIUM METABISULFITE ACS REAGENT ;… SODIUM DISULFITE DRY, RG, REAG ACS, REAG PH EUR;. SODIUM METABISULFITE, 97 +%, ACS REAGE NT; SODIUM METABISULFITE 97 +% ACS REAG &; SODIUM METABISULFITE REAGENT GRADE 97%; SodiumMetabisulphiteA.R;. SodiumMetabisulphiteFcc
Chinese alias
Sodium metabisulfite ; dipropylene sulfite ; weight thioredoxin ; pyrogallol sulfite ; sodium metabisulfite ; metabisulfite ; edible metabisulfite .
CASRN :7681-57-4
EINECS No. :231 -673-0
InchI Code : InChI = 1/2Na.H2O5S2/c;; 1-6 ⑵ 5-7 ⑶ 4 / h;; (H, 1,2) (H, 3,4) / q2 * +1 ;/ p-2
Formula : Na2S2O5
Molecular Weight : 190.09
Appearance: white or light yellow crystalline powder or small crystals ..
Specification: ≥ 65% of sulfur dioxide
Iron ≤ 0.005%
Water insoluble ≤ 0.05%
PH value of 4.0-4.6
Chemical Name
Chinese chemical name : sodium metabisulfite
Chemical Name : sodium metabisulfite
Chinese Name 2 : sodium metabisulfite
Name 2: sodium pyrosulfite / sodium metabisulphite
Technical Manual Code : 1333
CAS No. :7681-57-4
Formula : Na2S2O5
Molecular Weight : 190.09
Ingredients and composition
Hazardous components CAS No.
Sodium metabisulfite 7681-57-4
Category : Antioxidants .
Properties and Applications
Summary
Sodium metabisulfite ; sodium metabisulfite ; heavy thioredoxin ; Sodium metabisulfite; Sodium pyrosulfite formula Na2S2O5 Molecular Weight 190.10 CAS No. 7681-57-4
Physical and chemical properties
The main ingredients: pure
Appearance: colorless prismatic crystals or white powder ; has sulfur smell , sour, salty , ; Storage falling yellow color gradient .
pH:
300(fen jie) “>Melting point (℃):> 300 ( decomposition )
Boiling Point (℃): Not available
Relative density ( water = 1 ) : 1.48
Solubility: soluble in water , acidic aqueous solution ( at 20 ℃ to 54g/100ml water ; 100 ℃ when 81.7g/100ml water ) . Soluble in glycerol, slightly soluble in ethanol. The relative density of 1.4 . Soluble in water soluble in glycerine , slightly soluble in ethanol. Damp decomposition, exposed in air easily oxidized sodium . Contact with acid emit sulfur dioxide and generate the corresponding salts. Heated to 150 ℃ decomposition.
Stability and reactivity
Materials to avoid : strong acids, strong oxidizing agents.
Avoid contact conditions : moist air.
Physical and chemical properties
Sodium metabisulfite is white or yellow crystalline powder or small crystals , with a strong smell of SO2 , the proportion of 1.4 , dissolved in water , acidic aqueous solution , with a strong acid contact with the release SO2 and generates the corresponding salts, long home air, the oxidation into Na2S2O6, so the product can not go far. Higher than 150 ℃, namely decomposition SO2.
Security terms
S26In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S39Wear eye / face protection.
Wear goggles or masks.
S46If swallowed, seek medical advice immediately and show this container or label.
If swallowed , seek medical advice immediately and show this container or label.
Risk Phrases
R22Harmful if swallowed.
Harmful if swallowed .
R31Contact with acids liberates toxic gas.
Contact with acids liberates toxic gas.
R41Risk of serious damage to the eyes.
Serious damage to eyes .
Determination
Thiosulfate
Take this product 1.1g, slowly add dilute hydrochloric acid 10ml, dissolved in a water bath for 10 minutes , let cool, relocated colorimetric tube , add water to 20ml, as was muddy , and sodium thiosulfate solution ( 0.1 control solution mol / L) 0.20ml comparison is made using the same method , no thicker ( 0.2% ) .
Iron
Take this product 1.0g, 5ml of water and hydrochloric acid 2ml dissolved , evaporated on a water bath , the residue with water 15ml 2ml hydrochloric acid , dissolved , add the amount of bromine test solution and the solution of microscopic yellow , heated to remove excess bromine , let cool , add water to 25ml, according to inspection , 2.0ml solution compared with standard control solution made ​​of iron , not deeper ( 0.002% ) .
Heavy Metal
Take this product 1.0g, 10ml water dissolved, add 5ml of hydrochloric acid , evaporated on a water bath , the residue water 15ml, slowly boil for 2 minutes, filtered , and the filtrate was added so that the amount of bromine test solution clarified , heated to remove excess bromine , let cool, add 1 drop of phenolphthalein indicator solution and the amount of ammonia solution until the solution was pink , vinegar salt buffer (pH3.5) 2ml with water to make a 25ml, according to inspection , containing no heavy metals per million dated .
Arsenic

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U.S. new ethylene cracker production will reach 10

American Plastics News Network News, The Dow Chemical Company executives said, thanks to shale gas in North America to bring the advantages of raw material supply, the U.S. petrochemical market is being ushered in four wave of investment wave.
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